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Author contributions: P. The present study demonstrates HIV-1 Tat-mediated Kik sex Hollywood downregulation of microglial miR and its Bisman online Pico Rivera with microglial activation. Exposure of mouse primary microglia isolated from newborn pups of either sex to Adult store Montebello beach Tat resulted in decreased expression of primary miR, primary miR as well as the mature miR This was further validated in mouse primary microglial cells wherein HIV-1 Tat-mediated downregulation of miR resulted in increased expression of MECP2, leading in Bisman online Pico Rivera to further repression of miR via the feedback loop. In vitro findings were also confirmed in the basal ganglia of SIV-infected rhesus macaques both sexes.

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